The National Institute of Standards and Technology (NIST) hosts several tools and utilities to support HL7 messaging. The laboratory and its testing partners can use the NIST Validation Tool to validate test messages against the HL7 V2 Lab Results Interface (LRI) Guide, Release 1 or Release 2. As of April 2017, the Lab Orders Interface (LOI) Guide had not yet been added to the NIST Validation Tool. Note that the NIST Tool validates messages against the general LRI Guide and does not test the conformance of newborn screening messages specifically.

The NIST HL7 V2 Resource Portal is available at http://hl7v2tools.nist.gov