The Newborn Screening Contingency Plan Framework (known as the Framework) was developed in 2010 and the document was revised in 2015-16 in partnership with federal, state, local, and non-governmental organizations engaged in aspects of the newborn screening community. This is the first update to the Framework as it relates to newborn screening, which includes screening for hearing loss and Critical Congenital Heart Disease (CCHD). The intent of the Framework is to facilitate collaboration among federal agencies and state, local, territorial, tribal, and regional efforts to screen newborns for identified conditions during a public health emergency. This effort is limited to those areas of the newborn screening system (screening test, diagnosis and follow-up, treatment and management, evaluation, and education), for which the state public health agency assumes an oversight role.