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Effect of Dried Bloodspot Quality on Newborn Screening Analyte Concentrations and Recommendations for Minimum Acceptance Criteria for Sample Analysis

The analysis of dried bloodspots has been used routinely for newborn screening since the early 1970s, and the number of disorders screened has expanded substantially in recent years. However, there is a lack of evidence regarding minimum bloodspot quality acceptance criteria for sample analysis.This article analyzes the effect of dried bloodspot quality on newborn screening analyte concentrations and recommendations for minimum acceptance criteria for sample analysis. 

Title: Effect of Dried Bloodspot Quality on Newborn Screening Analyte Concentrations and Recommendations for Minimum Acceptance Criteria for Sample Analysis
Authors: Roanna S, George; Stuart J. Moat
Date: December 2015
Link: http://www.clinchem.org/content/early/2015/12/04/clinchem.2015.247668.ab...